Sarygamysh Lake. Sarygamysh Lake, also Sarykamysh or Sary-Kamysh, is the largest lake in Turkmenistan located about midway between the Caspian Sea and the Aral Sea. A quarter of the lake's area is in Uzbekistan. The Sarykamysh basin and the Sarykamysh delta of the Amu Darya river are physical and geographical nature regions of the Da??oguz Region of Turkmenistan.