Vatican City. Vatican City (/??v??t??k??n/), officially the Vatican City State (Italian: Stato della Citt?? del Vaticano; Latin: Status Civitatis Vaticanae), is an independent city-state, microstate and enclave within Rome, Italy. Also known as The Vatican, the state became independent from Italy in 1929 with the Lateran Treaty, and it is a distinct territory under "full ownership, exclusive dominion, and sovereign authority and jurisdiction" of the Holy See, itself a sovereign entity of international law, which maintains the city state's temporal, diplomatic, and spiritual independence. With an area of 49 hectares (121 acres) and a 2019 population of about 453, it is the smallest state in the world both by area and population. As governed by the Holy See, Vatican City State is an ecclesiastical or sacerd